Change of plans: CAR-t cell treatment out, onwards through the Stem Cell Transplant process
Life rarely goes as planned, and treatment is no exception. The plan was to administer some chemo to knock the leukemia back and then go on the car-t trial. However, the little amount I had put me in remission and now I’m off the car-t trial and prepping for stem cell transplant. The plan was to knock it back just a little (my bone marrow while I was in Swedish was reported at 30%--nothing to sneeze at), so Dr. Shustov ordered ¼ of the normal dose of Cytarabine, and removed another chemo from the typical induction dose, methotrexate, entirely. The “whiff” of cytarabine (Dr. Shustov’s word) apparently really connected with my leukemia cells and killed enough of them that I am in remission at the moment according to flow cytometry. Our hypothesis was that the leukemia this go around happened to be highly sensitive to cytarabine. Dr. Shustov was quite surprised that I was put into remission by such a weak dose. This is, of course, good news. However, it was not the plan, and when I first